Amazon SES for CiviCRM

Pre-requisites: DNS access

You now have two options for SMTP setup:

Alternatively, set up Postfix to relay through SES. I've done this successfully but neglected to document it, but know that it's possible.

Testing

SPECIAL NOTE FOR EC2 INSTANCES:
EC2 severely throttles outgoing mail on ports 25/465/587. You need to submit a request to Amazon to have this throttle lifted. This is separate from any user-configurable firewalling!